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Psoriasis
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Psoriasis is a common disease of the skin. It is a chronic inflammatory condition and it’s incidence in the United States is estimated to be between 0.25 and 2 percent.

What is Psoriasis?

Psoriasis of the skin is characterized by the occurrence of small, sharply delineated, dry papule, each covered by a delicate silvery scale which resembles just like a thin layer of mica. If the deep scales are removed, one or more tiny bleeding points are observed which is characteristic features and are termed as Auspitz’s sign. After removal of the scale the surface of the skin is red and dusky in the appearance of a few small papules, which gradually increase in size.

New lessions slowly arise over a period of weeks, months or even years. The popular enlarge at the periphery and becomes elevated. The smaller lesions joins with each other to form large plaques of irregular outline. They are roughly symmetrical and are most commonly seen on the extremities particularly on the elbows, knees, the scalp, back , chest, face and abdomen. Involvement of hands and feet is also observed but in rare cases. But the fingernails are not involved.

Causes of Psoriasis

The cause of Psoriasis is not exactly known. It has been known that heredity is a factor in some cases. Moreover, infection by various microorganisms, metablic disturbance, endocrine dysfunction neurogenic factors and trauma have been considered as an important precipitating factors in the onset of the disease. It has been seen that Psoriasis is also associated with WLA antigen itself or a linked gene.

Psoriatic patients have an increase in serum Igg and IgE are also increased in Psoriatic patients. Hence, we can say that autoimmunity is also related in Psoriasis. Psoriasis is more severe in winter and less severe in summer because of increased exposure to ultraviolet light. Patients who move to warm sunny climate usually undergo improvement in their condition. Mental anxiety or stress, increases the severity of the disease. Arthritis is a complication in about 12 percent of persons with Psoriasis. Psoriasis is uncommon in children. It is commonly seen in second and third decades of life. Social conditions or occupation does not play any role in the etiology of the disease.

Symptoms of Psoriasis

Oral lesions of Psoriasis are seen an the lips, bucca nucosa, palate, gingival and floor of the mouth. They may be seen as a gray or yellowish-white plaques or a silvery white, scaly lesions with an erythematous base or a popular eruptions which may be ulcerated. Psoriasis of the gingival was first observed by Orban and that of the alveolar ridge by Wooten. Generally, the findings in the oral lesions are similar to those in the skin lesions of psoriasis.

It has been that the ‘Psoriatic disease, may remain static for a long time, progress slowly to involve more and more skin are or may show sudden exacerbations. Commonly, the primary attack of Psoriasis occur after the age of 45 years. Male and females are equally affected by Psoriasis. It should be recommended that the case of mucosal involvement without any skin involvement must be viewed, with caution because the ‘Psoriasis Form” lesions of the oral mucosa includes psoriasis, Reiter’s syndrome, geographic tongue, benign migratory glossitis, etc.

Treatment of Psoriasis

The lesions of Psoriasis may be rarely pruritic, so it should be treated accordingly. The lesions may be few in number or sometimes extensive in distribution. The lesions often disappear spontaneously for varying periods but will nearly always secure. There is no specific form of therapy for Psoriasis. A variety of lotions and ointments have been classically prescribed.

Although, ultraviolet light is also prescribed. The most commonly used topical medicines are corticosteroids, tars, etc. Drugs such as Retinoic acid, iodochlorhydroxyquin, dihydroxyanthralin, to the Psoriatic patient. In general, however, we can say that any relief obtained is only symptomatic and temporary. It has been observed that the psoriasis is commonly cosmetically disfiguring. It even sometimes restricts the patient’s activities. But the disease does not lead to serious consequence.



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