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Multiple Sclerosis
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Multiple Sclerosis is an inflammatory disease of the Central Nervous System that is the brain and spinal cord. Chiefly, it is a disease of the “white mater” tissue.

The white matter is known to be made up of nerve fibres, which are responsible for transmitting communication signals both internally with in the Central Nervous System and between the Central Nervous System and the Nervous supplying rest of the body.

In people suffering from Multiple Sclerosis, patches of damaged called plaques or lesions are seen in the random areas of the CNS white matter. At the site of a lesion, a nerve insulating material, called myelin is lost. Clinically,

Multiple Sclerosis is a hard condition to characterize because it is very unpredictable and variable. No two people the same way and the expression of each individual’s disease is as unique as their fingerprints. In general, people with Multiples Sclerosis can experience partial or complete loss of any function that is controlled by, or passes through, the brain or spinal cord. Multiple Sclerosis is often known to be a very serious disease.

Causes of Multiple Sclerosis

During periods, of multiple sclerosis activity, white blood cells are drain to the regions of the white matter. This results in the developing of an inflammatory response, which is similar to what happens in the skin, when one gets pimple.

During the inflammation, the myelin gets stripped from the axons in a process known as demyelination. When the myelin sheath is damaged, then the transmission of nerve impulses is slowed stopped or can jump across into other demyelinated axons.

Additionally, the inflammation can also damage the underlying axonal membrane. Inflammation also kills the maintenance glial cell, that is it particularly kills the myelin-producing oligodendrocytes. Hence no oligodendrocytes persist in the middle of chronic Multiple Sclerosis lesions.

Symptoms of Multiple Sclerosis

The symptoms of Multiple Sclerosis may very greatly. The visual symptoms include generally, optic neuritis, Diplopia, Nystogmus, etc. In case of optic Neuritis, patient feel blurred vision, eye pain, loss of colour vision, blindness, etc.

In case of Diplopia, person experience double vision. In case of Nystagmus, jerky eye movements are felt. Motor Symptoms include Paresis, hemiplagia, Spasticity, Dysarthria, Muscle Atrophy, Foot drop, Restless Leg Syndrome, Spasms, Hypotonia, Myoclonus, etc.

Sensory Symptoms of Multiple Sclerosis includes, Par aesthesia, an aesthesia, Neuralgia, Tringeminal Neuralgia, etc. Bowel, Bladder and Sexual symptoms include frequent Micturation, Erectile dysfunction, Constipation, Fecal Incontinence, etc.




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