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Kerotocomus is defined as a bilateral, asymmetric non-inflammatory corneal ectasia. We can examine the relation between disease asymmetry and severity. Hence the method id examining the Keratocomus patients, none of the whom had under gone corneal surgery in either eye.

Disease asymmetry was determined by taking the difference between eyes for continuous variables. For categorical variables, asymmetry was categorized by whether the variable was present in neither, one or both eyes.

Disease severity was defined using the first definite apical clearance lens technique (FDACL). In this technique a rigid contact lens is used to measure corneal curvature from the worse, that is steeper eye.

Signs and Symptoms of Keratocomus

There were generally weak correlations between asymmetry and severity for low contrast habitual visual acuity, (that is r= 0.12, p=0.0003), high contrast habitual visual acuity (that is r=0.14, p< o.0002), and low contrast best corrected visual acuity (r= 0.21, p< 0.0001), and high contrast best corrected visual acuity (r=0.29, P< 0.0002).

Asymmetry in refractive error was more moderately correlated with disease severity, as was asymmetry in the flat and steep keratometric readings.

The average FDACL was significantly steeper in patients who had one eye with Vogt’s striae, Fleischer’s ring or corneal scarring compared when neither eye had these findings. Hence, we can conclude that the keratocomus patients with more severe disease are also more asymmetric in their disease status.

In earlier das, the interference regarding of keratocomus have been made by recording the frequency of unilateral cases of disease or unilateral corneal Keratocomus.

Comparison made between eye asymmetry associated with Keratocomus and the degree of asymmetry between the better and worse eyes in a group of myopic subjects. Large between eye differences were found in high and low contrast visual acuity, refractive error, kerotometry, and the first definite apical clearance lens (FDACL) measure of corneal curvature, especially compared with the normal myopic subjects.

Often at the time of diagnosis of kerotocomus, one eye is primarily affected, showing clinically measurable signs of the disease, while the other eye remains clear of these signs for several years. In other cases, larger degrees of between eye asymmetry in keratocomus seem to the associated with more severe cases of the disease.

High and low control visual acuity was also measured using the Bailey-Lovie visual acuity charts with habitual correction. Each eye was tested independently for habitual and best corrected visual acuity.

The total number of letters correctly identified was recorded. Manifest refraction was measured using standard clinical techniques. Larger lens power and cylindrical axis alternative measurement methods were used when patients had extremely poor vision.

Keratometry was used to measure the corneal power in the flat and steep meridians of both eyes two consecutive times and these measures were averaged.




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